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Genome-wide footprinting: ready for prime time?
High-throughput sequencing technologies have allowed many gene locus–level molecular biology assays to become genome-wide profiling methods. DNA-cleaving enzymes such as DNase I have been used to probe accessible chromatin. The accessible regions contain functional regulatory sites, including promot...
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| Publicado no: | Nat Methods |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5140282/ https://ncbi.nlm.nih.gov/pubmed/26914206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3766 |
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