Transcription factor assisted loading and enhancer dynamics dictate the hepatic fasting response

Fasting elicits transcriptional programs in hepatocytes leading to glucose and ketone production. This transcriptional program is regulated by many transcription factors (TFs). To understand how this complex network regulates the metabolic response to fasting, we aimed at isolating the enhancers and...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genome Res
Prif Awduron: Goldstein, Ido, Baek, Songjoon, Presman, Diego M., Paakinaho, Ville, Swinstead, Erin E., Hager, Gordon L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2017
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340970/
https://ncbi.nlm.nih.gov/pubmed/28031249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.212175.116
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