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Coordinate regulation of tetrahydrobiopterin turnover and phenylalanine hydroxylase activity in rat liver cells.

This work had two purposes: (i) to determine in vivo whether liver phenylalanine hydroxylase (PAH) is regulated by its substrates phenylalanine and tetrahydrobiopterin (BH4) as studies with purified enzyme suggest and (ii) to investigate in vivo the relationship between PAH activity and BH4 turnover...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Mitnaul, L J, Shiman, R
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42725/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7846072/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.3.885
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