Coordinate regulation of tetrahydrobiopterin turnover and phenylalanine hydroxylase activity in rat liver cells.

This work had two purposes: (i) to determine in vivo whether liver phenylalanine hydroxylase (PAH) is regulated by its substrates phenylalanine and tetrahydrobiopterin (BH4) as studies with purified enzyme suggest and (ii) to investigate in vivo the relationship between PAH activity and BH4 turnover...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Mitnaul, L J, Shiman, R
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1995
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42725/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7846072/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.3.885
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