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Altered Enzymes in Drug-Resistant Variants of Mammalian Tissue Culture Cells
Two selective procedures are compared in an effort to isolate variants of mouse L cells containing structural gene mutations. Among the resulting variant cloned cell lines are found two types of alterations in the enzyme hypoxanthine phosphoribosyl transferase (EC 2.4.2.8) (1): enzyme with altered k...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
1973
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427189/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4522295/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.11.3145 |
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