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Altered Enzymes in Drug-Resistant Variants of Mammalian Tissue Culture Cells

Two selective procedures are compared in an effort to isolate variants of mouse L cells containing structural gene mutations. Among the resulting variant cloned cell lines are found two types of alterations in the enzyme hypoxanthine phosphoribosyl transferase (EC 2.4.2.8) (1): enzyme with altered k...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Sharp, J. D., Capecchi, N. E., Capecchi, M. R.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1973
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427189/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4522295/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.11.3145
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