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Effect of Circularity and Superhelicity on Transcription from Bacteriophage λ DNA

We studied RNA synthesis in vitro from closed-circular λ DNA molecules with varying degrees of superhelicity. The four circular templates examined had 0, -50, -110, and -160 superhelical turns under the conditions of the transcription assay. We found that the total amount of RNA synthesis increases...

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Библиографические подробности
Главные авторы: Botchan, Peter, Wang, James C., Echols, Harrison
Формат: Artigo
Язык:Inglês
Опубликовано: 1973
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC427173/
https://ncbi.nlm.nih.gov/pubmed/4594034
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