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Fanconi Anemia Repair Pathway Dysfunction, a Potential Therapeutic Target in Lung Cancer
The Fanconi anemia (FA) pathway is a major mechanism of homologous recombination DNA repair. The functional readout of the pathway is activation through mono-ubiquitination of FANCD2 leading to nuclear foci of repair. We have recently developed an FA triple-staining immunofluorescence based method (...
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| Publicado no: | Front Oncol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4271581/ https://ncbi.nlm.nih.gov/pubmed/25566506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00368 |
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