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MicroRNA-34a is an important component of PRIMA-1-induced apoptotic network in human lung cancer cells
Restoration of p53 function in tumor cells would be an attractive strategy for lung cancer therapy because p53 mutations are found in more than 50% of lung cancers. The small molecule PRIMA-1 has been shown to restore the tumor suppression function of p53 and to induce apoptosis in human tumor cells...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4153870/ https://ncbi.nlm.nih.gov/pubmed/19921694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25049 |
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