Allosteric Inhibition of the Neuropeptidase Neurolysin

Neuropeptidases specialize in the hydrolysis of the small bioactive peptides that play a variety of signaling roles in the nervous and endocrine systems. One neuropeptidase, neurolysin, helps control the levels of the dopaminergic circuit modulator neurotensin and is a member of a fold group that in...

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Vydáno v:J Biol Chem
Hlavní autoři: Hines, Christina S., Ray, Kallol, Schmidt, Jack J., Xiong, Fei, Feenstra, Rolf W., Pras-Raves, Mia, de Moes, Jan Peter, Lange, Jos H. M., Melikishvili, Manana, Fried, Michael G., Mortenson, Paul, Charlton, Michael, Patel, Yogendra, Courtney, Stephen M., Kruse, Chris G., Rodgers, David W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Enzymology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271243/
https://ncbi.nlm.nih.gov/pubmed/25378390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.620930
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