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Dendritic Cell IL-1α and IL-1β Are Polyubiquitinated and Degraded by the Proteasome

IL-1α and β are key players in the innate immune system. The secretion of these cytokines by dendritic cells (DC) is integral to the development of proinflammatory responses. These cytokines are not secreted via the classical secretory pathway. Instead, 2 independent processes are required; an initi...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Biol Chem
मुख्य लेखकों: Ainscough, Joseph S., Frank Gerberick, G., Zahedi-Nejad, Maryam, Lopez-Castejon, Gloria, Brough, David, Kimber, Ian, Dearman, Rebecca J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271241/
https://ncbi.nlm.nih.gov/pubmed/25371210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.595686
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