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Dendritic Cell IL-1α and IL-1β Are Polyubiquitinated and Degraded by the Proteasome
IL-1α and β are key players in the innate immune system. The secretion of these cytokines by dendritic cells (DC) is integral to the development of proinflammatory responses. These cytokines are not secreted via the classical secretory pathway. Instead, 2 independent processes are required; an initi...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4271241/ https://ncbi.nlm.nih.gov/pubmed/25371210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.595686 |
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