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Depletion of the Central Metabolite NAD Leads to Oncosis-mediated Cell Death
Depletion of the central metabolite NAD in cells results in broad metabolic defects leading to cell death and is a proposed novel therapeutic strategy in oncology. There is, however, a limited understanding of the underlying mechanisms that connect disruption of this central metabolite with cell dea...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4271207/ https://ncbi.nlm.nih.gov/pubmed/25355314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.580159 |
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