Histone deacetylase 5 interacts with Krüppel-like factor 2 and inhibits its transcriptional activity in endothelium

AIMS: Vascular endothelial dysfunction and inflammation are hallmarks of atherosclerosis. Krüppel-like factor 2 (KLF2) is a key mediator of anti-inflammatory and anti-atherosclerotic properties of the endothelium. However, little is known of the molecular mechanisms for regulating KLF2 transcription...

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Bibliographic Details
Published in:Cardiovasc Res
Main Authors: Kwon, Il-Sun, Wang, Weiye, Xu, Suowen, Jin, Zheng-Gen
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4271065/
https://ncbi.nlm.nih.gov/pubmed/25096223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvu183
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