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Endonuclease-induced, targeted homologous extrachromosomal recombination in Xenopus oocytes.

Homologous recombination in gene targeting in most organisms occurs by an inefficient mechanism. Inducing a double-strand break in the chromosomal target may increase this efficiency by allowing recombination to proceed by the highly efficient single-strand annealing mechanism. A gene targeting expe...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Segal, D J, Carroll, D
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1995
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42709/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7846056/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.3.806
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