Endonuclease-induced, targeted homologous extrachromosomal recombination in Xenopus oocytes.
Homologous recombination in gene targeting in most organisms occurs by an inefficient mechanism. Inducing a double-strand break in the chromosomal target may increase this efficiency by allowing recombination to proceed by the highly efficient single-strand annealing mechanism. A gene targeting expe...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
1995
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42709/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7846056/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.3.806 |
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