The orphan nuclear receptor NR4A1 specifies a distinct subpopulation of quiescent myeloid-biased long-term HSCs

Hematopoiesis is maintained throughout life by self-renewing hematopoietic stem cells (HSCs) that differentiate to produce both myeloid and lymphoid cells. The NR4A family of orphan nuclear receptors, which regulates cell fate in many tissues, appears to play a key role in HSC proliferation and diff...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Stem Cells
Auteurs principaux: Land, Ruben H., Rayne, Anna K., Vanderbeck, Ashley N., Barlowe, Trevor S., Manjunath, Shwetha, Gross, Matthew, Eiger, Sophie, Klein, Peter S., Cunningham, Nicole R., Huang, Jian, Emerson, Stephen G., Punt, Jennifer A.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270858/
https://ncbi.nlm.nih.gov/pubmed/25284014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1852
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires