Selective In Vivo Targeting of Human Liver Tumors by Optimized AAV3 Vectors in a Murine Xenograft Model

Current challenges for recombinant adeno-associated virus (rAAV) vector–based cancer treatment include the low efficiency and the lack of specificity in vivo. rAAV serotype 3 (rAAV3) vectors have previously been shown to be ineffective in normal mouse tissues following systemic administration. In th...

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Bibliographische Detailangaben
Veröffentlicht in:Hum Gene Ther
Hauptverfasser: Ling, Chen, Wang, Yuan, Zhang, Yuanhui, Ejjigani, Anila, Yin, Zifei, Lu, Yuan, Wang, Lina, Wang, Meng, Li, Jun, Hu, Zhongbo, Aslanidi, George V., Zhong, Li, Gao, Guangping, Srivastava, Arun, Ling, Changquan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2014
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270149/
https://ncbi.nlm.nih.gov/pubmed/25296041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2014.099
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