Superresolution Modeling of Calcium Release in the Heart

Stable calcium-induced calcium release (CICR) is critical for maintaining normal cellular contraction during cardiac excitation-contraction coupling. The fundamental element of CICR in the heart is the calcium (Ca(2+)) spark, which arises from a cluster of ryanodine receptors (RyR). Opening of these...

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Detalles Bibliográficos
Publicado en:Biophys J
Autores principales: Walker, Mark A., Williams, George S.B., Kohl, Tobias, Lehnart, Stephan E., Jafri, M. Saleet, Greenstein, Joseph L., Lederer, W.J., Winslow, Raimond L.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2014
Materias:
Systems Biophysics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269784/
https://ncbi.nlm.nih.gov/pubmed/25517166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.11.003
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