Dynamics of Calcium Sparks and Calcium Leak in the Heart

We present what we believe to be a new mathematical model of Ca(2+) leak from the sarcoplasmic reticulum (SR) in the heart. To our knowledge, it is the first to incorporate a realistic number of Ca(2+)-release units, each containing a cluster of stochastically gating Ca(2+) channels (RyRs), whose bi...

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Bibliografiset tiedot
Päätekijät: Williams, George S.B., Chikando, Aristide C., Tuan, Hoang-Trong M., Sobie, Eric A., Lederer, W.J., Jafri, M. Saleet
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Biophysical Society 2011
Aiheet:
Biological Systems and Multicellular Dynamics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177068/
https://ncbi.nlm.nih.gov/pubmed/21943409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.07.021
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