IGF-1 deficiency impairs cerebral myogenic autoregulation in hypertensive mice

Aging impairs autoregulatory protection in the brain, exacerbating hypertension-induced cerebromicrovascular injury, neuroinflammation, and development of vascular cognitive impairment. Despite the importance of the age-related decline in circulating insulin-like growth factor-1 (IGF-1) levels in ce...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Toth, Peter, Tucsek, Zsuzsanna, Tarantini, Stefano, Sosnowska, Danuta, Gautam, Tripti, Mitschelen, Matthew, Koller, Akos, Sonntag, William E, Csiszar, Anna, Ungvari, Zoltan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269740/
https://ncbi.nlm.nih.gov/pubmed/25248835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.156
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