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BASIC—ALIMENTARY TRACT: Loss of Parietal Cell Expression of Sonic Hedgehog Induces Hypergastrinemia and Hyperproliferation of Surface Mucous Cells
BACKGROUND & AIMS: Sonic Hedgehog (Shh) is expressed in the adult stomach, but its role as a gastric morphogen is unclear. We sought to identify mechanisms by which Shh might regulate gastric epithelial cell function and differentiation. METHODS: Mice with a parietal cell–specific deletion of Sh...
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| Wydane w: | Gastroenterology |
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| Główni autorzy: | , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2009
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4269486/ https://ncbi.nlm.nih.gov/pubmed/19909751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.11.002 |
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