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Sustained Induction of Fetal Hemoglobin by Pulse Butyrate Therapy in Sickle Cell Disease

High levels of fetal hemoglobin (Hb F) protect from many of the complications of sickle cell disease and lead to improved survival. Butyrate and other short chain fatty acids were previously shown to increase Hb F production in erythroid cells in vitro and in animal models in vivo. However, butyrate...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Atweh, George F., Sutton, Millicent, Nassif, Imad, Boosalis, Vassiliki, Dover, George J., Wallenstein, Sylvan, Wright, Elizabeth, McMahon, Lillian, Stamatoyannopoulos, George, Faller, Douglas V., Perrine, Susan P.
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269326/
https://ncbi.nlm.nih.gov/pubmed/10068649
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