Butyrate increases the efficiency of translation of γ-globin mRNA

Fetal hemoglobin (Hb F) levels increase in most patients with sickle cell disease following intermittent butyrate therapy. Although the full effects of butyrate on Hb F levels usually require multiple treatment cycles, in some patients a peak level is achieved after a few days of butyrate therapy. O...

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Bibliografiske detaljer
Main Authors: Weinberg, Rona S., Ji, Xinjun, Sutton, Millicent, Perrine, Susan, Galperin, Yelena, Li, Qiliang, Liebhaber, Stephen A., Stamatoyannopoulos, George, Atweh, George F.
Format: Artigo
Sprog:Inglês
Udgivet: 2004
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826269/
https://ncbi.nlm.nih.gov/pubmed/15479724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-02-0454
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