Pre-immature dendritic cells (PIDC) pulsed with HPV16 E6 or E7 peptide are capable of eliciting specific immune response in patients with advanced cervical cancer

BACKGROUND: The protein products of the early genes E6 and E7 in high-risk HPV types 16 and 18 have been implicated in the oncogenic capability of these viruses. Therefore, these peptides represent attractive vaccine therapy targets. METHODS: Thirty-two patients with advanced cervical cancer (HPV16...

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Veröffentlicht in:J Transl Med
Hauptverfasser: Rahma, Osama E, Herrin, Vincent E, Ibrahim, Rami A, Toubaji, Anton, Bernstein, Sarah, Dakheel, Omar, Steinberg, Seth M, Eid, Rasha Abu, Mkrtichyan, Mikayel, Berzofsky, Jay A, Khleif, Samir N
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269078/
https://ncbi.nlm.nih.gov/pubmed/25510844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-014-0353-4
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