Selection of Unadapted, Pathogenic SHIVs Encoding Newly Transmitted HIV-1 Envelope Proteins

Infection of macaques with chimeric viruses based on SIV(MAC) but expressing the HIV-1 envelope (Env) glycoproteins (SHIVs) remains the most powerful model for evaluating prevention and therapeutic strategies against AIDS. Unfortunately, only a few SHIVs are currently available. Furthermore, their g...

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Published in:Cell Host Microbe
Main Authors: Del Prete, Gregory Q., Eilers, Braiden, Moldt, Brian, Keele, Brandon F., Estes, Jacob D., Rodriguez, Anthony, Sampias, Marissa, Oswald, Kelli, Fast, Randy, Trubey, Charles M., Chertova, Elena, Smedley, Jeremy, LaBranche, Celia C., Montefiori, David C., Burton, Dennis R., Shaw, George M., Markowitz, Marty, Piatak, Michael, KewalRamani, Vineet N., Bieniasz, Paul D., Lifson, Jeffrey D., Hatziioannou, Theodora
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268878/
https://ncbi.nlm.nih.gov/pubmed/25211081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.08.003
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