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Cardiac Titin and Heart Disease
The giant sarcomeric protein titin is a key determinant of myocardial passive stiffness and stress sensitive signaling. Titin stiffness is modulated by isoform variation, phosphorylation by protein kinases and possibly oxidative stress through disulfide bond formation. Titin has also emerged as an i...
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| Publicado no: | J Cardiovasc Pharmacol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4268868/ https://ncbi.nlm.nih.gov/pubmed/24072177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000007 |
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