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Cardiac Titin and Heart Disease

The giant sarcomeric protein titin is a key determinant of myocardial passive stiffness and stress sensitive signaling. Titin stiffness is modulated by isoform variation, phosphorylation by protein kinases and possibly oxidative stress through disulfide bond formation. Titin has also emerged as an i...

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Bibliografische gegevens
Gepubliceerd in:J Cardiovasc Pharmacol
Hoofdauteurs: LeWinter, Martin M., Granzier, Henk L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268868/
https://ncbi.nlm.nih.gov/pubmed/24072177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000007
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