Intracellular immunization of human fetal cord blood stem/progenitor cells with a ribozyme against human immunodeficiency virus type 1.

Successful treatment of human immunodeficiency virus infection may ultimately require targeting of hematopoietic stem cells. Here we used retroviral vectors carrying the ribozyme gene to transduce CD34+ cells from human fetal cord blood. Transduction and ribozyme expression had no apparent adverse e...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Yu, M, Leavitt, M C, Maruyama, M, Yamada, O, Young, D, Ho, A D, Wong-Staal, F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42687/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7531339/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.3.699
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