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Aberrant methylation of the SPARC gene promoter and its clinical implication in gastric cancer

Secreted protein acidic and rich in cysteine (SPARC) gene has been shown to be epigenetically silenced in several cancers. We investigated the loss of expression and promoter methylation of this tumor suppressor gene in gastric cancers and correlated the data with clinicopathological features. We ob...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chen, Zi-Yi, Zhang, Jun-Ling, Yao, Hong-Xin, Wang, Peng-Yuan, Zhu, Jing, Wang, Wei, Wang, Xin, Wan, Yuan-Lian, Chen, Shan-Wen, Chen, Guo-Wei, Liu, Yu-Cun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268651/
https://ncbi.nlm.nih.gov/pubmed/25516351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07035
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