Secreted Protein Acidic and Rich in Cysteine (SPARC) Suppresses Angiogenesis by Down-Regulating the Expression of VEGF and MMP-7 in Gastric Cancer

BACKGROUND: Secreted protein acidic and rich in cysteine (SPARC) is a glycoprotein that functions to inhibit angiogenesis, proliferation, and invasion in different types of cancer. The ability of SPARC to modulate neovascularisation is believed to be mediated in part by its ability to modulate the e...

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Detalhes bibliográficos
Main Authors: Zhang, Jun-Ling, Chen, Guo-Wei, Liu, Yu-Cun, Wang, Peng-Yuan, Wang, Xin, Wan, Yuan-Lian, Zhu, Jing, Gao, Hong-Qiao, Yin, Jie, Wang, Wei, Tian, Mao-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434168/
https://ncbi.nlm.nih.gov/pubmed/22957090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044618
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