Aberrant methylation of SPARC in human lung cancers

SPARC (secreted protein acidic and rich in cysteine) is an extracellular Ca(2+)-binding matricellular glycoprotein associated with the regulation of cell adhesion and growth. We investigated loss of expression of SPARC gene and promoter methylation in lung cancers and correlated the data with clinic...

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Detalhes bibliográficos
Main Authors: Suzuki, M, Hao, C, Takahashi, T, Shigematsu, H, Shivapurkar, N, Sathyanarayana, U G, Iizasa, T, Fujisawa, T, Hiroshima, K, Gazdar, A F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361924/
https://ncbi.nlm.nih.gov/pubmed/15756262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602376
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