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Sall4 overexpression blocks murine hematopoiesis in a dose-dependent manner

Sall4 is a transcription factor that exists in two splice isoforms – Sall4a and Sall4b – and regulates transcription in embryonic stem cells, hematopoiesis and acute myeloid leukemia. Constitutive overexpression of Sall4 in mice induces acute myeloid leukemia. Interestingly, a potential benefit of u...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Exp Hematol
Egile Nagusiak: Milanovich, Samuel, Peterson, Jonathan, Allred, Jeremy, Stelloh, Cary, Rajasekaran, Kamalakannan, Fisher, Joseph, Duncan, Stephen, Malarkannan, Subramaniam, Rao, Sridhar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268405/
https://ncbi.nlm.nih.gov/pubmed/25246269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2014.09.004
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