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Sall4 overexpression blocks murine hematopoiesis in a dose-dependent manner
Sall4 is a transcription factor that exists in two splice isoforms – Sall4a and Sall4b – and regulates transcription in embryonic stem cells, hematopoiesis and acute myeloid leukemia. Constitutive overexpression of Sall4 in mice induces acute myeloid leukemia. Interestingly, a potential benefit of u...
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| Publicado en: | Exp Hematol |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4268405/ https://ncbi.nlm.nih.gov/pubmed/25246269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2014.09.004 |
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