Signaling in Effector Lymphocytes: Insights toward Safer Immunotherapy

Receptors on T and NK cells systematically propagate highly complex signaling cascades that direct immune effector functions, leading to protective immunity. While extensive studies have delineated hundreds of signaling events that take place upon receptor engagement, the precise molecular mechanism...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Rajasekaran, Kamalakannan, Riese, Matthew J., Rao, Sridhar, Wang, Li, Thakar, Monica S., Sentman, Charles L., Malarkannan, Subramaniam
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863891/
https://ncbi.nlm.nih.gov/pubmed/27242783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00176
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