Astrocyte elevated gene-1 (AEG-1) interacts with Akt isoform 2 to control glioma growth, survival and pathogenesis

The oncogene AEG-1 (MTDH) is highly expressed in glioblastoma multiforme (GBM) and many other types of cancer, where it activates multiple signaling pathways that drive proliferation, invasion, angiogenesis, chemoresistance, radioresistance and metastasis. AEG-1 activates the Akt signaling pathway a...

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Bibliografiske detaljer
Udgivet i:Cancer Res
Main Authors: Hu, Bin, Emdad, Luni, Bacolod, Manny D., Kegelman, Timothy P., Shen, Xue-Ning, Alzubi, Mohammad A., Das, Swadesh K., Sarkar, Devanand, Fisher, Paul B.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268375/
https://ncbi.nlm.nih.gov/pubmed/25304263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-2978
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