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AEG-1–AKT2: A novel complex controlling the aggressiveness of glioblastoma
Expression of AEG-1 (also known as MTDH or LYRIC) is elevated in many cancers including glioblastoma multiforme (GBM), in which it functions as an oncogene. AEG-1 activates AKT signaling and physically interacts with AKT2 in GBM. Disruption of this interaction reduces glioma cell survival and invasi...
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| Publicado no: | Mol Cell Oncol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905313/ https://ncbi.nlm.nih.gov/pubmed/27308476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723556.2014.995008 |
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