Whole exome sequencing of muscle-invasive bladder cancer identifies recurrent mutations of UNC5C and prognostic importance of DNA repair gene mutations on survival

PURPOSE: Due to suboptimal outcomes in muscle-invasive bladder cancer even with multimodality therapy, determination of potential genetic drivers offers the possibility of improving therapeutic approaches and discovering novel prognostic indicators. EXPERIMENTAL DESIGN: Using pTN staging, we case-ma...

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Detaylı Bibliyografya
Yayımlandı:Clin Cancer Res
Asıl Yazarlar: Yap, Kai Lee, Kiyotani, Kazuma, Tamura, Kenji, Antic, Tatjana, Jang, Miran, Montoya, Magdeline, Campanile, Alexa, Yew, Poh Yin, Ganshert, Cory, Fujioka, Tomoaki, Steinberg, Gary D., O’Donnell, Peter H., Nakamura, Yusuke
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268280/
https://ncbi.nlm.nih.gov/pubmed/25316812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-0257
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