Whole exome sequencing of muscle-invasive bladder cancer identifies recurrent mutations of UNC5C and prognostic importance of DNA repair gene mutations on survival

PURPOSE: Due to suboptimal outcomes in muscle-invasive bladder cancer even with multimodality therapy, determination of potential genetic drivers offers the possibility of improving therapeutic approaches and discovering novel prognostic indicators. EXPERIMENTAL DESIGN: Using pTN staging, we case-ma...

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Bibliografske podrobnosti
izdano v:Clin Cancer Res
Main Authors: Yap, Kai Lee, Kiyotani, Kazuma, Tamura, Kenji, Antic, Tatjana, Jang, Miran, Montoya, Magdeline, Campanile, Alexa, Yew, Poh Yin, Ganshert, Cory, Fujioka, Tomoaki, Steinberg, Gary D., O’Donnell, Peter H., Nakamura, Yusuke
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268280/
https://ncbi.nlm.nih.gov/pubmed/25316812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-0257
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