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Comparison of exome-based HLA class I genotyping tools: identification of platform-specific genotyping errors

Accurate human leukocyte antigen (HLA) genotyping is critical in studies involving the immune system. Several algorithms to estimate HLA genotypes from whole-exome data were developed. We compared the accuracy of seven algorithms, including Optitype, Polysolver and PHLAT, as well as investigated pat...

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Detalles Bibliográficos
Publicado en:J Hum Genet
Main Authors: Kiyotani, Kazuma, Mai, Tu H, Nakamura, Yusuke
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334549/
https://ncbi.nlm.nih.gov/pubmed/27881843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jhg.2016.141
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