Identification of Disease-Promoting HLA Class I and Protective Class II Modifiers in Japanese Patients with Familial Mediterranean Fever

OBJECTIVES: The genotype-phenotype correlation of MEFV remains unclear for the familial Mediterranean fever (FMF) patients, especially without canonical MEFV mutations in exon 10. The risk of FMF appeared to be under the influence of other factors in this case. The contribution of HLA polymorphisms...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yasunami, Michio, Nakamura, Hitomi, Agematsu, Kazunaga, Nakamura, Akinori, Yazaki, Masahide, Kishida, Dai, Yachie, Akihiro, Toma, Tomoko, Masumoto, Junya, Ida, Hiroaki, Koga, Tomohiro, Kawakami, Atsushi, Eguchi, Katsumi, Furukawa, Hiroshi, Nakamura, Tadashi, Nakamura, Minoru, Migita, Kiyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431852/
https://ncbi.nlm.nih.gov/pubmed/25974247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125938
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