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BAG3 facilitates the clearance of endogenous tau in primary neurons

Tau is a microtubule associated protein that is found primarily in neurons, and in pathological conditions such as Alzheimer disease (AD) it accumulates and contributes to the disease process. Since tau plays a fundamental role in the pathogenesis of AD and other tauopathies, and in AD mouse models...

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Podrobná bibliografie
Vydáno v:Neurobiol Aging
Hlavní autoři: Lei, Zhinian, Brizzee, Corey, Johnson, Gail V.W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268232/
https://ncbi.nlm.nih.gov/pubmed/25212465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.08.012
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