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Identification of the WNT1 residues required for palmitoylation by Porcupine

The post-translational palmitoylation of WNT morphogens is critical for proper signaling during embryogenesis and adult homeostasis. The addition of palmitoyl groups to WNT proteins is catalyzed by Porcupine (PORCN). However, the Wnt amino acid residues required for recognition and palmitoylation by...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:FEBS Lett
Prif Awduron: Miranda, M., Galli, L.M., Enriquez, M., Szabo, L.A., Gao, X, Hannoush, R.N., Burrus, L.W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268045/
https://ncbi.nlm.nih.gov/pubmed/25451226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2014.11.016
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