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Differential Palmit(e)oylation of Wnt1 on C93 and S224 Residues Has Overlapping and Distinct Consequences

Though the mechanisms by which cytosolic/intracellular proteins are regulated by the post-translational addition of palmitate adducts is well understood, little is known about how this lipid modification affects secreted ligands, such as Wnts. Here we use mutational analysis to show that differentia...

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Detalles Bibliográficos
Main Authors: Galli, Lisa M., Burrus, Laura W.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202554/
https://ncbi.nlm.nih.gov/pubmed/22046319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026636
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