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Differential Palmit(e)oylation of Wnt1 on C93 and S224 Residues Has Overlapping and Distinct Consequences

Though the mechanisms by which cytosolic/intracellular proteins are regulated by the post-translational addition of palmitate adducts is well understood, little is known about how this lipid modification affects secreted ligands, such as Wnts. Here we use mutational analysis to show that differentia...

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Bibliografske podrobnosti
Main Authors: Galli, Lisa M., Burrus, Laura W.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202554/
https://ncbi.nlm.nih.gov/pubmed/22046319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026636
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