Protein-tyrosine-phosphatase SHPTP2 is a required positive effector for insulin downstream signaling.
SHPTP2 is a ubiquitously expressed tyrosine-specific protein phosphatase that contains two amino-terminal Src homology 2 (SH2) domains responsible for its association with tyrosine-phosphorylated proteins. In this study, expression of dominant interfering mutants of SHPTP2 was found to inhibit insul...
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| Yayımlandı: | Proc Natl Acad Sci U S A |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
1995
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42680/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7531337/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.3.664 |
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