Differential regulation of the alpha/beta interferon-stimulated Jak/Stat pathway by the SH2 domain-containing tyrosine phosphatase SHPTP1.

Interferons (IFNs) induce early-response genes by stimulating Janus family (Jak) tyrosine kinases, leading to tyrosine phosphorylation of Stat transcription factors. Previous studies implicated protein-tyrosine phosphatase (PTP) activity in the control of IFN-regulated Jak/Stat signaling, but the sp...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	David, M, Chen, H E, Goelz, S, Larner, A C, Neel, B G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230960/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8524272/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.12.7050
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