Protein-tyrosine-phosphatase SHPTP2 is a required positive effector for insulin downstream signaling.

SHPTP2 is a ubiquitously expressed tyrosine-specific protein phosphatase that contains two amino-terminal Src homology 2 (SH2) domains responsible for its association with tyrosine-phosphorylated proteins. In this study, expression of dominant interfering mutants of SHPTP2 was found to inhibit insul...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Yamauchi, K, Milarski, K L, Saltiel, A R, Pessin, J E
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1995
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42680/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7531337/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.3.664
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