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Profiling small RNA reveals multimodal substructural signals in a Boltzmann ensemble

As the biomedical impact of small RNAs grows, so does the need to understand competing structural alternatives for regions of functional interest. Suboptimal structure analysis provides significantly more RNA base pairing information than a single minimum free energy prediction. Yet computational en...

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Pubblicato in:Nucleic Acids Res
Autori principali: Rogers, Emily, Heitsch, Christine E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267672/
https://ncbi.nlm.nih.gov/pubmed/25392423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku959
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