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Profiling small RNA reveals multimodal substructural signals in a Boltzmann ensemble

As the biomedical impact of small RNAs grows, so does the need to understand competing structural alternatives for regions of functional interest. Suboptimal structure analysis provides significantly more RNA base pairing information than a single minimum free energy prediction. Yet computational en...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Rogers, Emily, Heitsch, Christine E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267672/
https://ncbi.nlm.nih.gov/pubmed/25392423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku959
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