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Loss of loop adenines alters human telomere d[AG(3)(TTAG(3))(3)] quadruplex folding
Abasic (AP) lesions are the most frequent type of damages occurring in cellular DNA. Here we describe the conformational effects of AP sites substituted for 2′-deoxyadenosine in the first (ap7), second (ap13) or third (ap19) loop of the quadruplex formed in K(+) by the human telomere DNA 5′-d[AG(3)(...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nucleic Acids Res |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Oxford University Press
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4267657/ https://ncbi.nlm.nih.gov/pubmed/25428355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1245 |
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